Isolation and Purification of Ginkgolide A, B and Bilobalide
- VernacularTitle:银杏内酯A、B和白果内酯的分离与纯化
- Author:
Jinyu HAH
;
Qiaowei CHU
;
Heying CHANG
;
Hua WANG
;
Haijing WANG
- Publication Type:Journal Article
- Keywords:
ginkgolide bilobalide preparative liquid chromatography
- From:
Chinese Traditional and Herbal Drugs
2000;31(9):652-653
- CountryChina
- Language:Chinese
-
Abstract:
A simple method for the isolation and purification of ginkgolide A, B and bilobalide(ginkgo terpene trialctone) was developed. A commercially available extract of leaves of Ginkgo biloba L.containing ＞6％ ginkgo terpene trilactone was used as the raw material. After partition in EtOAc, the en-riched extract was separated to give individual terpenes by preparative liquid chromatography. GinkgolideA, B and bilobalide could be isolated with high purity by recrystallizing in MeOH-H2O.
