Effects of Panax Pseudo-ginseng on the Liver in SMAO Shocked Rabbits
- VernacularTitle:三七根总皂甙对SMAO休克家兔肝脏的保护作用
- Author:
Ling GAO
;
Shining WEN
;
Tongzeng HU
- Publication Type:Journal Article
- Keywords:
Panax pseudo-ginseng Shock Liver
- From:
The Journal of Clinical Anesthesiology
2000;16(12):613-614
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To study the effects of panax pseudo-ginseng on the liver in rabbits suffered from SMAO shock.Methods:20 rabbits were divided randomly into control group and treatment group. SMAO (superior mesenteric artery occlusion)shock model was made by occluding the superior mesenteric artery for 1 hour. In treatment group, 200 mg/kg of panax pseudo-ginseng diluted in normal saline was given intravenously. In control group, the same volume of normal saline without drug was given intravenously. Mean blood pressures and 4-hour survival rates were monitored during the study. Biopsies from the left lobe of the liver were taken from all animals at the end of the study for microstructure study using electro-microscope.Results:Compared to control group, animals in the treatment group had a significant prolonged survival time and improved mean blood pressures. Impairment of hepatocytes in treatment group was significantly reduced. Conclusion: Panax pseudo-ginseng has benefit effects on the liver. This plays an important role in prolonging the survival time of the rabbits with SMAO shock.
