Clinical Research on Infectious Complications after Hematopoietic Stem Cell Transplantation
- VernacularTitle:造血干细胞移植感染并发症防治的临床研究
- Author:
Quanshun WANG
;
Bolong ZHANG
;
Fangding LOU
;
Qi ZHOU
;
Li YU
;
Haichuan LIU
;
Shanqian YAO
- Publication Type:Journal Article
- From:
Chinese Journal of Nosocomiology
2001;11(1):10-12
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE To evaluate retrospectively the incidence and treatment of infectious complications within the first 60 days after hematopoietic stem cell transplantation,and to find more efficient anti-infective regimens. METHODS To study the incidence,pathogenic microorganism,prophylaxis,treatments of infectious complications in 150 patients accepted hematopoietic stem cell transplantation from April 1984 to March 1998 in our hospital.The results were analyzed statistically.RESULTS Incidence of infectious complications was 89.3% in all 150 cases.Three patients(2%) died of the fungal infection.The incidence of the infections was 32.5% in patients accepted treatment with imipenem or／and ceftazidine,and 15.7% in other patients without the treatment with imipenem or／and ceftazidine(P＜0.02).CONCLUSIONS The strong antibacterial prophylaxis can′t reduce the incidence of infection,and may increase the chance of fungal infection.
