Effects of Alcohol Extract of Herba Epimedii on the Release of NO from Human Umbilical Vein Endothelial Cells in Vitro
- VernacularTitle:淫羊藿醇提物对内皮细胞释放 NO 的影响
- Author:
Yao XU
;
Guowu BIAN
;
Minyu WU
- Publication Type:Journal Article
- Keywords:
@Herba Epimedii/pharmacology;
impotence/TCD therapy;
e ndothelial cell/drug effect;
nitric oxide;
@serologic pharmacology
- From:
Traditional Chinese Drug Research & Clinical Pharmacology
2001;12(1):38-40
- CountryChina
- Language:Chinese
-
Abstract:
To investigate the mechanism of Herba Epimedii alcoho l extract for imp otence, Giess reagent was used to observe the effect of the alcohol extract of H erba Epimedii in mice and its effect on release of NO fro m human umbilical vein endothelial cells in vitro was also studied. The results showed that alcoh ol extract of Herba Epimdii had no effect on the release of NO. But the serum co llected from the mice after the medication of alcohol extract of Herba Epimedii for 120min and 180min promoted the production of NO, and the reaction reached th e peak at 120 min. It is indicated that the promotion of NO release from endothe lial cells may be one of the mechanisms of Herba Epimedii for impotence.
