The experimental animal models of intrauterine growth retardation
- VernacularTitle:胎儿宫内生长迟缓的实验动物模型
- Author:
Guangliang CHEN
;
Lei ZHANG
;
Qinmao WANG
- Publication Type:Journal Article
- From:
Chinese Pharmacological Bulletin
2001;17(1):108-110
- CountryChina
- Language:Chinese
-
Abstract:
AIM This paper was to review the methods of establishing experimental animal models of intrauterine growth retardation (IUGR) and their observed index. METHODS Passive smoking, passive smoking plus drinking wine, NG nitro-L-arginine methyl ester, dactinomycin, thiamine deficiency plus pyrithiamine, or ligating the uterine artery during pregnancy were used.RESULT The fatal and maternal body weight was lower body length; was shorter; infant physique and nerve system development was slow.CONCLUSION The above methods could establish animal models of IUGR.
