mRNA Expression of c-myc Gene in the Hyperacute Rejection of Xe notransplantation
- VernacularTitle:c-myc基因信使核糖核酸在异种移植超急性排斥反应中的表达
- Author:
Qiang MENG
;
Qingyu WU
- Publication Type:Journal Article
- From:
Chinese Circulation Journal
2001;16(1):67-69
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To research expression and function of c-myc gene in hyperacute r ejection of xenotransplantation. Method:Through the model of hyperacute rejection of xenotransplantation wit h isolated rat heart perfused with human plasma,we detected c-myc mRNA expressi on and cell localization with in situ hybridization in hyperacute rejection. Result:c-myc mRNA increased expression in the endothelium cell of heart.Th e value of signal is 450.09±409.99.The value of signal of group of control is 1 74.40±51.50(p＜0.05)。 Conclusion:From these study findings,it would appear that hyperacute rejecti on is associated with the elevation of c-myc mRNA expression.
