Study of the Relation of Serum Angiotensin Converting Enzyme and Pregnanacy-induced Hypertension
- VernacularTitle:血管紧张素转化酶活性与妊高征病因关系的研究
- Author:
Yan WANG
;
Tao SHANG
;
Yanxiang LIU
;
Jian WU
;
Peng LI
- Publication Type:Journal Article
- From:
Journal of China Medical University
2001;30(1):69-71
- CountryChina
- Language:Chinese
-
Abstract:
Objective:Our purpose was to investigate the function of angiotensis converting enzyme(ACE) in the occurrence and development of pregnancy-induced hypertension(PIH). Methods:The study group included 30 pregnant women diagnosed with PIH( 10 mild, 10 moderate, 10 severe). Thirty healthy pregnant women were selected as the control group. The serum was assayed for the activity of ACE by using color comparison method, hippuric acid used as the substrate. Results:The activity of ACE of the study group was significantly higher than that of the control group. Significantly positive correlationships existed between mean blood pressure, degree of adema, level of urine protein,and uric acid. Conclusion:The elevation of serum activity of ACE is related to the occurrence and development of PIH.
