Clinical Investigation of Soluble Tumor Necrosis Factor Receptor-Ⅰ in Serum of Patients with Acute Tuberculosis
- VernacularTitle:活动性结核病人血清sTNFR-Ⅰ变化的临床研究
- Author:
Jin LIU
;
Liyun LI
- Publication Type:Journal Article
- From:
Journal of China Medical University
2001;30(1):36-37
- CountryChina
- Language:Chinese
-
Abstract:
Objective: Our purpose was to study the concentration of soluble tumor necrosis factor receptor-Ⅰ(sTNFR-Ⅰ) in the serum of patients with acute tuberculosis. Methods: The levels of soluble TNFR-Ⅰ in serum were measured in 11 patients with acute tuberculosis. Concentration of sTNFR-Ⅰ were measured by using enzyme-linked immunological binding assay. Results: In patients with acute tuberculosis, especially severe tuberculosis, serum levels of sTNFR-Ⅰ increased significantly (P<0.01), compared with those of control. After antituberculosis therapy, serum levels of sTNFR-Ⅰin patients with acute tuberculosis decreased by various degrees. Conclusion: Measurements of sTNFR-Ⅰ in serum of patients with acute tuberculosis could be an important index in the judgement of the outcome of the disease.
