Clinical application of propofol in critical patients with mechanical ventilation after major operation
- VernacularTitle:大手术后机械通气的危重病人异丙酚的临床应用
- Author:
Bao LIU
;
Shaohui CHENG
;
Jinquan WANG
;
Xiaogen TAO
- Publication Type:Journal Article
- Keywords:
propofol;
mechanical ventilation;
epinephrine;
norepinephrine;
operation
- From:
Chinese Journal of Clinical Pharmacology and Therapeutics
2001;6(1):49-50
- CountryChina
- Language:Chinese
-
Abstract:
Aim To evaluate the clinical application of propofol in critical patients with mechanical ventilation. Methods22 patients with mechanical ventilation after major operation were randomly divided into control group and propofol group patient in the propofol group were continually transfused with propofol by micro pump. Clinical manifestations, blood pressure, heart rate and the concentration of epinephrine (E)and norepinephrine (NE) in patients of both groups were observed. Results The patients in propofol group were all in sleeping state, while those in the control group had evidently higher blood pressure,heart rate and the concentration of epinephrine and norepinephrine after wearing of ventilator. There was a significant difference between the two groups ( P＜0.05) . Conclusion Propofol can make the critical patients quiet and inasleepingstate,inhilitthereleaseof epinephrine and norepinephrine, which rescdt in hemodynamic stability.
