Study on stability of human serum γ-globulin products
- VernacularTitle:提高人血丙种球蛋白制品稳定性方法的研究
- Author:
Qizhong WANG
;
Shunlong ZHANG
;
Xihe LI
;
Guanfen XU
- Publication Type:Journal Article
- From:
Chinese Journal of Biochemical Pharmaceutics
2001;22(1):23-24
- CountryChina
- Language:Chinese
-
Abstract:
Purpose The aim is to increase stability and to s olve the problem of splitting of human serum γ-globulin products.Methods Fibrinolysin and profibrinolysin in the human serum γ-globulin p roducts were absorbed with L-lysine-Sepharose 4B.Results Compared with the unabsorbed products, the splitting degree of the absorbed pr oducts decreased obviously.Conclusion In manufacture of human serum γ-globulin products,absorbing fibrinolysin and profibrinolysin with L -lysine-Sepharose 4B may increase stability of the product.It was an effecti ve method to improve the quality of product.