Effect of laparoscopic cholecystectomy on systemic stress response
- VernacularTitle:腹腔镜胆囊切除术对机体应激反应的影响
- Author:
Heping ZENG
;
Guxiang YE
;
Fangfang PAN
;
Yibao ZHAO
- Publication Type:Journal Article
- Keywords:
CHOLECYSTECTOMY,LAPAROSCOPY;
INTERLEUKIN-1/blood;
TUMOR NECROSIS FACTOR/blood;
C-REACTIVE PROTEIN/blood;
INTERLEUKIN-6/blood
- From:
Chinese Journal of General Surgery
2001;10(1):35-37
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the systemic stress responses of laparoscopic cholecystectomy(LC). Methods Seventy patients with cholecystolithiasis were randomly divided into two groups: LC and open cholecystectomy(OC). Peripheral blood samples were obtained during the preoperative day and 1, 3, 5, 7 day after operation. Serum cytokines levels (TNF-α, IL-1β and IL-6) and C-reactive protein(CRP) were measured. Results Changes of TNF-α and IL-1β before or after surgery in both groups showed no significant difference(P>0.05). Serum concentrations of IL-6 and CRP after surgery in both groups were significantly higher than those before surgery(P<0.05); but there were no significant difference between the two groups(P>0.05). Conclusions The systemic stress responses of LC have no significant difference comparing with OC.
