Clinical study on relationship between gallbladder carcinoma and gallstone
- VernacularTitle:结石性胆囊炎癌变高危因素的临床研究
- Author:
Fenglin ZHAO
;
Jingsen SHI
;
Ge CHEN
;
Liansuo ZHOU
;
Yijun YANG
;
Yue HAN
- Publication Type:Journal Article
- Keywords:
CHOLECYSTITIS/compl;
CHOLELITHIASIS/compl;
GALLBLADPER NEOPLASMS/etiol
- From:
Chinese Journal of General Surgery
2001;10(1):38-41
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the risk factors of gallbladder stone changing to gallbladder carcinoma. Methods The clinical data of 200 patients with gallbladder stone undergoing operation were retrospective analysed. Results (1) In the 200 resected gallbladder specimens, gallbladder mucosa hyperplasia was found in 144 specimens(72%), atypical hyperplasia(AHP) in 38(19%), infiltrative cancer in 7(3.5%). All the paracancer mucosa had midder or severe AHP. The incidence of atypical hyperplasia and canceration had increased with patients' age and the history lenth of cyst stone. (2) The content of DNA, the porpotion of euplpoid cells, the AgNOR content in tissues as follows: hyperplasia