SFE-CGC DETERMINATION OF TANSHINONE IN SALVIA MILTIORRHIZA BUNGE
- VernacularTitle:丹参中丹参酮IIA的SFE-CGC法测定
- Author:
Bin CHEN
;
Mei ZHU
;
Wongxing XING
;
Lili LIU
;
Yutian WU
- Publication Type:Journal Article
- From:
Acta Pharmaceutica Sinica
2001;36(1):55-57
- CountryChina
- Language:Chinese
-
Abstract:
AIM To analyze tanshinone IIA in Salvia miltiorrhiza Bunge by supercritical fluid extraction (SFE) coupled with capillary gas chromatography (CGC). METHODS The solution pressure was predicted by solubility parameter theory, the extraction conditions were confirmed by orthogonal design in which temperature, volume of modifier and dynamic extracting volume had been studied in three levels. RESULTS This method is quick, convenient, precise and accurate, added sample recovery is 95.3%, RSD=4.27%. CONCLUSION Compared with the method of ultrasonic extraction, significantly better qualitative and quantitative result could be obtained by SFE-CGC and expend less organic solvent then make less pollution.
