Comparative study on the effects of collagenase inhibitor in different eye drops
- VernacularTitle:几种胶原酶抑制剂滴眼液的效果比较
- Author:
Yuanping SHEN
;
Luo ZHANG
;
Zheng HU
- Publication Type:Journal Article
- Keywords:
collagenase;
collagenase inhibitor;
comassie brilliant blue colorimetric method;
cartopril
- From:
Recent Advances in Ophthalmology
2000;20(6):426-427
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate, compare and filtrate the collagenase inhibitor effects among six kinds of eye drops for clinical use.Methods The collagenase inhibitor’s effects were detected by rat's collagen and collagenase with comassie brilliant blue colorimetric method.Results The inhibitting collagenase effects among six kinds of eye drops were different: the effect of cartopril was the strongest；the acetylcysteine and sodium edetate were more strong and the sodium citrate, sodium hyposulfite and tetracycline were less strong.Conclusion 0.5g*L-1cartopril eye drops has stronger efficacy to inhibit collagenase, with less side effect or stimulation，more convenient resource and preparation than other eye drops.
