Effects of Shenyanling on chronic glomerulonephritis in rabbits
- VernacularTitle:肾炎灵冲剂对家兔慢性肾小球肾炎的作用
- Author:
Shuxun CUI
;
Jiping LI
;
Qiujing WANG
;
Shijie YANG
- Publication Type:Journal Article
- Keywords:
Steblay nephritis;
Shenyanling;
rabbit
- From:
Journal of Jilin University(Medicine Edition)
2000;26(6):589-591
- CountryChina
- Language:Chinese
-
Abstract:
Objective :To sutdy the effects of Shenyanling on chronic glomerulonephritis in rabbits. Meth-ods:Rat glomerular base membrane (GBM) and Freund＇s adjuvant were injected into rabbits subcuta-neously or intracutaneously to build the Steblay nephritis model. Shenyanglin was administered. Kidneyfunction was evaluated by measuring urine protein,urea nitrogen ,creatinine ,albumin and globulin in serumas wellas the histopathological changes of kidney were observed. Results:Compared with model group,Shenyanling could dose-dependently reduce the level of the urine protein,urea nitrogen and creatinine inserum and the damage of kidney;while,the serum albumin could maintain the normal level (P＜0.05).Conclusion:Shenyanling has protective effects on chronic glomerulonephritis in rabbits.
