Biomembrane Signal Transduction and Apoptosis
- VernacularTitle:生物膜信号转导与细胞凋亡
- Author:
Hong XIN
;
Guangtao YAN
;
Banzao CHEN
- Publication Type:Journal Article
- From:
Progress in Biochemistry and Biophysics
2001;28(1):52-55
- CountryChina
- Language:Chinese
-
Abstract:
A variety of extra-cellular signals could activate the target molecules and induce the associated biological effects depended on different signal pathways. Apoptosis, or programmed cell death, is a conservation process essential for normal development and homeostasis of biologist. It's known that a number of factors and pathways can lead to apoptosis. Specific phosphorlipids and proteins of biomembrane could activate the signal cascades of apoptosis. The interaction of caspases, bcl-2 family and mitochondria play an essential role in regulation of apoptosis.