Immunohistochemical Study of Insulin-Like Growth Factor-I in Human Fetal Organs
- VernacularTitle:胰岛素样生长因子-I在胎儿肝、肾等组织的分布
- Author:
Fan WANG
;
Huijun YANG
;
Ruixiang LI
;
Aidong LI
- Publication Type:Journal Article
- From:
Progress of Anatomical Sciences
2001;7(1):27-29
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the distribution of insulin-like Growth Factors (IGFs) in liver、 spleen、kidney、thymus and supraadrenal glands of fetus from 16 to 24 weeks.Method Using ABC immunohistochemistry. Results IGF-I positive cells were found in these organs during this period of fetal life, but the differences of number and reaction intensity of IGF-I positive cells appeared in different organs and individuals.Conclusion These organs tissues can express IGF-I during fetal development and play paracrine and/or autocrine role in cellular proliferation and differentiation of these fetal tissue.
