Homology evaluation of 53 clinical strains of M. Chel onae abscessus subspecies by using pulsed-field gel electrophoresis
- VernacularTitle:53株龟分支杆菌脓肿亚种临床分离株的同源性研究
- Author:
Qinghua HU
;
Liangcheng LI
- Publication Type:Journal Article
- From:
Chinese Journal of Disease Control & Prevention
2001;5(1):25-26
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate homology of 53 clinical str ains of M. chelonae abscessus subspecies which caused the nosocomial infecti on. Methods Large restriction fragment (LRF) pattern analysis of genomic DNA by using pulsed-field gel electrophoresis was performed and differences of patterns were compared. Results 53 clinical strains had two types of LRF pat terns. 49 strains had the same one LRF pattern, the rest 4 had another pattern. Conclusions The nosocomial postoperative M. Chelonae absc essus subspecies outbreak was mainly caused by the same infectious source. So pulsed-field gel electrophoresis was suitable for evaluating strain homolo gy and looking for infectious sourses.
