A Preliminary Pharmacodynamic Study on the Preparation of Artificial Fel Serpentis and Bulbus Fritiliariae Cirrhosae
- VernacularTitle:人工蛇胆川贝制剂的药效学初步研究
- Author:
Xiamin HU
;
Chaozhou SHI
- Publication Type:Journal Article
- Keywords:
@ Shedan Chuanbei San/pharmacology;
@artificial Fel Serpentis and Bulbus Fritiliariae Cirrhosae/ pharmacology;
Cough/TCD therapy
- From:
Traditional Chinese Drug Research & Clinical Pharmacology
2001;12(2):95-97
- CountryChina
- Language:Chinese
-
Abstract:
The preliminary pharmacodynamic studies of the prepar ation of artificial Fel Serpentis and Bulbus Fritiliariae Cirrhosae and Shedan Chuanbei San (composed of natural Fel Serpentis and Bulbus Fri tiliariae Cirrhosae) were reported.The results showed that both of the above pre parations could prolong the cough latency and decrease cough frequeucies induced by ammonia within 3 min,promote the excretion of respiratory tract,increase the excretion of phenol red and inhibit auricular edema induced by xylol in mice. M eanwhile, the above two preparations could also inhibit Ach-induced tracheospasm in vitro.Therefore,the replacement of natural Fel Serpentis with the artificial in the preparation of Shedan Chuanbei San is reasonable.