Anti-inflammatory, Analgesic and Immunosuppressive Action of Niuhuang Qianjin San
- VernacularTitle:牛黄千金散抗炎镇痛和免疫抑制作用
- Author:
Qingrong XU
;
Na LI
;
Guanhua DU
- Publication Type:Journal Article
- Keywords:
@ Niuhuang Qianjin San (NQS)/pharma cology;
@Analagisic and immunosuppressive action;
Immunosuppression;
Rats;
Mice
- From:
Traditional Chinese Drug Research & Clinical Pharmacology
2001;12(2):98-100
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To study the anti-inflammatory, analgesic and immunosuppressive action of Niuhuang Qianjin San (NQS). M ethods: The anti-inflammatory action of NQS was studied by the methods of rat pa w swelling and mouse ear swelling and the analgesic action by mouse body torsion method and K+ subcutaneous penetration method in rats.Immunosuppressive effec t was evaluated by peripheral T lymphocyte percentage, splenic lymphocyte transfor mation ratio, phagocytic function of intraperitoneal magocytes, the activity of delayed hypersensitivity, serum hemolysin level and the function of antibody-yie lding cells in mice. Results: NQS could obviously alleviate inflammation, increa se codeine's analgesic action and suppress immunity. The difference were signif icant (P<0.01) as compared with normal saline contr ol group.Conclusion:NQS exerts certain anti-inflammatory,analagisic and immunosu ppressive action.
