Experiment of inhibition of Cronassial to Glu during ischemia reperfusion of rat
- VernacularTitle:大鼠急性脑缺血再灌注损伤中康络素对谷氨酸抑制作用的实验研究
- Author:
Songyan LIU
;
Qing ZHAO
;
Jing WANG
- Publication Type:Journal Article
- From:
Journal of Jilin University(Medicine Edition)
2001;27(1):37-38
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To study the Cronassial′protective effect on brain tissue during ischemia reperfusion.Methods:The rat cerebral ischemia reperfusion model was prepared by four-vessel occulasion method.The Glu,GABA content in hippocampus during cerebral ischemia reperfusion was observed by high press liquid phase method.Results:Glu,GABA content increased during ischemia and decreased during reperfusion. Cronassial could obviously decrease the Glu content and increase neuron density.Conclusion:Cronassial can inhibit Glu and protect brain tissue during cerebral ischemia reperfusion.