Fenoterol and ipratropium bromide inhalation alone or combined in treatment of childhood acute paroxysm of asthma
- VernacularTitle:非诺特罗及异丙托溴铵单用或联用吸入治疗小儿哮喘发作
- Author:
Qun LIU
;
Jiawei ZHANG
;
Jie LIN
;
Jing ZHANG
- Publication Type:Journal Article
- From:
Chinese Journal of New Drugs and Clinical Remedies
2001;20(2):135-136
- CountryChina
- Language:Chinese
-
Abstract:
AIM:To observe the effect of fenoterol and ipratropium bromide alone or combined in the treatment of childhood acute paroxysm of asthma. METHODS: Ninty-five children with acute paroxysm of asthma were divided into 3 groups:group A of 30 children (age 6 a ±s 4 a) received 0.5% fenoterol 2-6 a 0.1 mL, 6-14 a 0.2 mL; group B of 30 children (age 7 a±3 a) received 0.025% ipratropium bromide 2-6 a 0.5 mL, 6-14 a 1 mL; group C of 35 children (age 6 a±3 a) received the same dosage of fenoterol+ipratropium bromide as the other two groups. The drug in 3 groups diluted with 0.9% sodium chloride to 3 mL, aerosol inhalation spray inhalation, tid, for 2-5 d. RESULTS: The obvious effective rate 63% in group A was similar to that of group B 60% (P>0.05), but was lower than that of group C 86% (P<0.05). The adverse reaction wasn't found in 3 groups. CONCLUSION: In treating the childhood acute paroxysm of asthma, the effect of fenoterol is similor with ipratropium bromide, but the combination drug gives a better therapy than either drug alone.
