Recent progress in the studies on taxol
- VernacularTitle:紫杉醇的最新研究进展
- Author:
Jinhui YUAN
;
Lixia GUO
;
Xingwang WANG
;
Hong XIE
- Publication Type:Journal Article
- From:
Chinese Pharmacological Bulletin
2001;17(2):135-139
- CountryChina
- Language:Chinese
-
Abstract:
Taxol could induce tumor cell apoptosis throug h activation of Fas/FasL and caspases. bcl-2 also played an important role in t axol-induced cell apoptosis. Furthermore, taxol had the similar action with lip opolysaccharide on inducing the release of bioactive substances including tumor necrosis factor, interleukin and nitric oxide. There were as well some progresse s in taxol-resistance of tumor cells.
