Mechanisms of heterogeneous electrophysiology in heart and the relation to electropharmacology and toxicology
- VernacularTitle:心脏不均一电生理机理与电药理学和毒理学的关系
- Author:
Guirong LI
;
Yiyue CHEN
- Publication Type:Journal Article
- From:Chinese Journal of Pharmacology and Toxicology
2001;15(2):95-104
- CountryChina
- Language:Chinese
-
Abstract:
It is believed that cardiac electrophysiological properties are not homogeneous, and the heterogeneity exists between pacemaker and conduction cells, atrial and ventricular cells, and among endocardium, midmyocardium, and epicardium of the transmural ventricular wall. The heterogeneous electrophysiology is related to the differential distribution and expression of transmembrane ionic channels. The present review involves literatures regarding the intrinsic biological basis of cardiac heterogeneous electrophysiology.
