Comparison Between Clarithromycin and Erythromycin in Treating Respiratory Tract Mycoplasmal Infections of Children
- VernacularTitle:克拉霉素与红霉素治疗小儿呼吸道支原体感染的对比研究
- Author:
Rong FU
;
Guocheng ZHANG
;
Xinhong QIAN
- Publication Type:Journal Article
- From:
China Pharmacy
2001;12(2):101-102
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To compare the effect and adverse reactions of clarithromycin(Limaixian,CT)with those of erythromycin(ET)in treating respiratory tract mycoplasmal infections of children.METHODS:98 patients were randomly divided into CT group(56 cases)and ET group(42 cases),CT in oral dosage of 20mg/(kg.d)and ET in iv dosage of 30~40mg/(kg· d)were given respectively.RESULTS:The curative rate,effective rate and clearance of mycoplasma of CT group were higher than those of ET group with significant differences(P<0.05).The adverse reactions induced by oral CT were less than those by iv infused ET(P<0.01).CONCLUSION: Oral CT shows satisfactory therapeutic effect, less adverse reactions and can effectively clear away mycoplasma in treatment of respiratory tract mycoplasmal infections of childhood.