Comparison Between Clarithromycin and Erythromycin in Treating Respiratory Tract Mycoplasmal Infections of Children
- VernacularTitle:克拉霉素与红霉素治疗小儿呼吸道支原体感染的对比研究
- Author:
Rong FU
;
Guocheng ZHANG
;
Xinhong QIAN
- Publication Type:Journal Article
- From:
China Pharmacy
2001;12(2):101-102
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE：To compare the effect and adverse reactions of clarithromycin(Limaixian，CT)with those of erythromycin(ET)in treating respiratory tract mycoplasmal infections of children.METHODS：98 patients were randomly divided into CT group(56 cases)and ET group(42 cases)，CT in oral dosage of 20mg/(kg.d)and ET in iv dosage of 30～40mg/(kg· d)were given respectively.RESULTS：The curative rate，effective rate and clearance of mycoplasma of CT group were higher than those of ET group with significant differences(P<0.05).The adverse reactions induced by oral CT were less than those by iv infused ET(P<0.01).CONCLUSION： Oral CT shows satisfactory therapeutic effect， less adverse reactions and can effectively clear away mycoplasma in treatment of respiratory tract mycoplasmal infections of childhood.
