Diagnosis and treatment of acute rejection of liver transplantation (a report of 2 cases)
- VernacularTitle:肝移植术后急性排斥反应的诊治(附2例报告)
- Author:
Tiemin ZHANG
;
Hongchi JIANG
;
Haiquan QIAO
;
Jun XU
;
Shuzhi GE
;
Wenyan TANG
;
Bei SUN
- Publication Type:Journal Article
- From:
Chinese Journal of General Surgery
2001;10(2):152-154
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the diagnosis and treatment of acute rejection of orthotopic liver transplantation (OLT). Methods From July 1999 to April 2000, two piggyback liver transplantations were performed on two patients with Wilson's disease. Results Cyclosporine A, azathioprine and methylprednisolone were the baseline immunosuppression management. Acute rejection occured 5 times in the 2 patients. The correct diagnosis was obtained through clinical inspection, liver function test and biopsy. The rejections were controlled by intensive steriod therapy plus OKT3 or FK506. Conclusions Clinical inspection and liver function test can suggest the episode of acute rejection in time. Hepatic biopsy is the key point for diagnosis of acute rejecton, Reasonable use of immunosppression is critical for the treatment.
