Anticipated value of ICGR15 and OGTT for hepatic reserving function in patients with primary hepatic cancer
- VernacularTitle:ICGR15和OGTT预测肝癌患者肝脏储备功能的价值
- Author:
Youming DING
;
Aimin ZHANG
;
Feng YAO
;
Jikui LIU
- Publication Type:Journal Article
- From:
Chinese Journal of General Surgery
2001;10(2):162-165
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study anticipated value of the retention rate of indocyanine green at 15 minutes after injection (ICGR15) and oral glucose tolerance test (OGTT) on hepatic function reserve in patients with primary hepatic cancer (PHC). Methods 58 patients with PHC were divided into 3 groups according to the recovery after operation for PHC. Of them, 29 cases showed good recovery (group A), 18 mild liver dysfunction (group B) and 11 severe liver dysfunction (group C) respectively. ICGR 15, OGTT, routine liver function tests were performed in all patients preoperatively. Results ICGR15 in group C(24.17%±6.59%) obviously increased than that in group A(11.42%±3.91%,P<0.01) and in group B(16.28±6.07%, P<0.01). Blood glucose lever of 120 min after glucose loading test in group C (9.91 mmol/L±3.09 mmol/L)was significantly higher than that in group A(5.42 mmol/L±0.83 mmol/L, (P<0.01)and group B(6.68±1.61, P<0.01). The accuracy (81.0%,86.2%), positive (90.6%, 93.5%) and negative prediction value (72.5%, 74.4%) of OGTT and ICGR 15 were respectively significent greater than those of Pugh's scoring (P<0.01).Conclusions ICGR15 and OGTT are worthwhile indicators to assess hepatic function reserve for patients with PHC. Combination of both ICGR15 and OGTT has higher predictive value on hepatic function reserve.
