Effect of thymopeptide on LPS-induced release of nitric oxide from mouse peritoneal microphase in vitro
- VernacularTitle:胸腺肽对小鼠腹腔巨噬细胞释放一氧化氮的影响
- Author:
Yang JI
- Publication Type:Journal Article
- From:
Chinese Journal of Biochemical Pharmaceutics
2001;22(2):74-75
- CountryChina
- Language:Chinese
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Abstract:
Purpose The aim is to investigate the effects of thymopeptide on LPS-induced release of nitric oxide (NO) from mouse peritoneal microphase in vitro.Methods NO was detected by Griess reagent.Results Thymopeptide 83.3～333.3 μg/ml reduced NO synthesis and secretion from mouse peritoneal microphase in vitro significantly.Conclusion The effects of thymopeptide on LPS-induced release of NO from mouse peritoneal microphase may be one of mechanisms of its pharmacological effect.
