Evaluating cerebral blood flow autoregulation by critical closing pressure.
- VernacularTitle:临界关闭压在脑血流动力学评价中的应用
- Author:
Qingchun GAO
;
Ruxun HUANG
;
Jinsheng ZENG
;
Zhenpei SU
;
Yingxian CHEN
;
Jianwen CHEN
- Publication Type:Journal Article
- From:
Chinese Journal of Nervous and Mental Diseases
2001;27(2):109-111
- CountryChina
- Language:Chinese
-
Abstract:
Objective To establish a new practical method to assess the cerebral blood flow autoregulation. Methods We assessed the flow velociey of middle cerebral artery with transcranial Doppler and recorded invasively the blood presure simultaneonsly. Then on the basis of critical closing pressure (CCP), the lower limit of cerebral blood flow autoregulation and the blood flow resistance of arterioles were calculated.The data compared with the results generated by routine method. Results The lower limit of autoregulation working out by CCP was 70.88±24.05 mmHg, which was similar to the result measured by routine method. The lower limit of autoregulation and the arteriole resistance in RHR were significantly higher than those of normal controls, and highly relate to arterial blood pressure significantly, especially pulse pressure. Conclusions The physiology and pathology of cerebral blood flow can be evaluated conveniently and accurately by assessment of the lower limit of autoregulation and arterioles resistance with CCP.
