Effect of Paroxetine in Treatment of Depressive Patients with Grave's Disease
- VernacularTitle:帕罗西汀治疗伴情绪障碍甲亢患者的临床观察
- Author:
Haichen YANG
;
Yonglin SUN
;
Dexin ZANG
- Publication Type:Journal Article
- From:
Chinese Mental Health Journal
2001;15(2):123-124
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To study depression of patients with Grave's disease and the therapeutic effect of Paroxetine (antidepressant). Method: 82 patients with first onset Grave's disease were collected and 52 of them had depression. The depressive patients were divided into Paroxetine and control group. All cases had the same anti-hyperthyroidism treatment. Result: 63.4% (52/82) patients with first onset Grave's disease had depression before Paroxetine treatment. After 4 weeks and 8 weeks treatment, Paroxetine group had greater decrease in FT3 and FT4, and lower scores of SDS and SAS than control group (p＜0.01). Conclusion: Paroxetine does enhance the therapeutic effect of anti-hyperthyroidism, as well as improving depression of patients with first-onset Grave's disease.
