A Novel Model for DNA Replication and Transcription
- VernacularTitle:一种新的DNA复制和转录模型
- Author:
Hanbo ZHANG
;
Huasun DING
- Publication Type:Journal Article
- Keywords:
replication;
transcription;
sliding model;
factory mode
- From:
Progress in Biochemistry and Biophysics
2001;28(2):148-151
- CountryChina
- Language:Chinese
-
Abstract:
In two models for DNA replication and transcription, tra ditional one known as sliding model postulates that proteins involving replicati on and transcription track on the DNA template as a locomotive. In factory model proposed recently, those proteins are immobilized on nuclear structure, to pull the template. Growing evidence from biochemistry, biophysics, and cell biology suggests that the factory model is an actual fact in vivo.