Effect of Cilazapril on Reactivity of Blood Vessels in Diabetic Rats
- VernacularTitle:一平苏对糖尿病大鼠血管反应性的影响
- Author:
Xuan WANG
;
Junqian LI
;
Jie CHANG
;
Dehong CAI
;
Pingsheng WU
- Publication Type:Journal Article
- From:
Chinese Journal of Hypertension
2001;9(2):152-153
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effect of cilazapril on reactivit y of blood vessels in diabetic rats. Methods The mesenteric vessels of streptozotocin induced diabetic rats wer e perfused with Kreb-Ringer's solution in vitro,the mesenteric vessels reactivi ty of diabetic rats was measured by physiological recorder. Results The responsive continual time to norepinephrine was delay ed signific antly(9.4±3.1 vs 5.2±2.1,P<0.01) and the highest perfusion pressu re decrease significantly in diabetic rats(5.12±0.87 vs 7.81±0.92 kPa, P<0.01); When taken cilazapril showed no difference in these indexes in diabetic animal s.
