Dyspeptic Symptom Severity Related to Helicobacter pylori and Stress in Functional Dyspepsia.
- Author:
Cheol Hwan KIM
1
;
Ho Cheol SHIN
;
Yong Woo PARK
;
Haeng LEE
Author Information
1. Department of Family Medicine, Sungkyunkwan University School of Medicine.
- Publication Type:Original Article
- Keywords:
Functional dyspepsia;
Helicobacter pylori;
Stress
- MeSH:
Biopsy;
Dyspepsia*;
Family Practice;
Helicobacter pylori*;
Helicobacter*;
Mass Screening;
Mood Disorders;
Psychology;
Surveys and Questionnaires
- From:Journal of the Korean Academy of Family Medicine
2000;21(1):28-37
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND: It is well-known that dyspeptic symptoms in functional dyspepsia are related to psychological factors such as stress and mood disorder. But it is still controversial whether H. pylori infection is a important factor for functional dyspepsia. We conducted this study to investigate whether H. pylori infection or stress are related to dyspeptic symptom severity in functional dyspepsia. METHODS: From Mar. 1 1999 to Apr. 30 1999, attendees to a Health Screening Center and a Family Practice Center were eligible study subjects. The subjects were responded to questionnaire including dyspeptic symptom severity items and BEPSI-K(stress scale). And among eligible subjects, one hundred and thirty two diagnosed with functional dyspepsia by gastrofibroscopy were final study subjects. H. pylori infection was confirmed by antral biopsies & smear (Giemsa stain). RESULTS: In functional dyspepsia, high BEPSI-K score group(upper tertile) complained more severe dyspeptic symptom severity than low BEPSI-K score group(lower tertile) after adjusted for other variables(adjusted OR=8.389, 95% C.I.=2.232-31.231). But the dyspeptic symptom severity was not associated with H. pylori infection status (adjusted OR=1.514, 95% C.I.=0.567-4.046). CONCLUSIONS: The dyspeptic symptom severity in functional dyspepsia was associated with stress but not with H. pylori infection status.
