Seroprevalence of hepatitis B virus markers among adult in a Youngdong area of Kwangwon Province.
- Author:
Mi Kyeong OH
1
;
Jong Sung KIM
;
Yong Bin LEE
;
Joo Hyun HAN
Author Information
1. Department of Family Medicine, Asan Kangnung Hospital.
- Publication Type:Original Article
- Keywords:
Hepatitis B Virus;
HBsAg;
Prevalence;
Epidemiology;
Adult
- MeSH:
Adult*;
Asian Continental Ancestry Group;
Biomarkers;
Chungcheongnam-do;
Delivery of Health Care;
Epidemiology;
Fibrosis;
Gangwon-do*;
Hepatitis B Surface Antigens;
Hepatitis B virus*;
Hepatitis B*;
Hepatitis*;
Hepatitis, Chronic;
Humans;
Immunization;
Korea;
Prevalence;
Radioimmunoassay;
Seroepidemiologic Studies*;
Vaccination
- From:Journal of the Korean Academy of Family Medicine
2000;21(1):91-99
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND: Hepatitis B is a leading cause of chronic hepatitis, cirrhosis, and hepatocelluar carcinoma. It is a well-known fact that Korea is one of the hyperenedemic areas of Hepatitis B virus among East Asian countries. Many pnst reports have shown that positive rate of HBsAg in Korea was about 6-14%. But precise data for Yongdong area of Kwangwon Province in Korea was lacking. Here authors report on the prevalence of viral markers of hepatitis B among adults in this area. method: Sera were collected from 7469 residents in Yongdong area of Kwangwon Province who visited the Health Care Center, Asan Kangnung Hospital from September 11th to August 31th. HBsAg, AntiHBc-IgG, and AntiHBs were tested by radioimmunoassay. RESULTS: Positive rate of HBsAg of total study subjects was 8.5%, and was significantly decreased as age increased, and higher in males(10.2%) than in females(6.6%). Positive rate for one or more markers among HBsAg, AntiHBc-IgG, and AntiHBs was 84%, and was significantly increased as age increased, and higher in males(86.2%) than in females(81.2%). All negative rate for HBsAg, AntiHBc-IgG, and AntiHBs was 16.0% and all positive rate was 0.5%. Positive rate of AntiHBc-IgG without HBsAg and AntiHBs was 15.7% Positive rate of AntiHBs without HBsAg and AntiHBc-IgG was 11.7%. Positive rate of AntiHBc-IgG and AntiHBs was 72.1% and 60.2%, respectively. CONCLUSIONS: There was no significant difference in positive rate of HBsAg between this study for residents in Yongdong area of Kwangwon Province and past many reports. 84% of the total study subjects showed serological evidence of previous exposure to hepatitis B virus (HBV) naturally exposed or by vaccine immunization. 16% of the total study subjects was a proper candidate for hepatitis B vaccination.
