Pharmacokinetics of thymopeptide in rabbit
- VernacularTitle:胸腺肽在家兔体内的药代动力学
- Author:
Haisong ZHANG
;
Xiaojun ZOU
;
Ke XU
;
Deguang CHEN
- Publication Type:Journal Article
- From:
Chinese Journal of Biochemical Pharmaceutics
2001;22(3):132-133
- CountryChina
- Language:Chinese
-
Abstract:
Purpose The aim is to study the pharmacokinetic of iv thymopeptide in rabbit.Method Thymopeptide concentration of rabbit plasma was determined by HPLC and pharmacokinetic parameters were computerized with 3P87 program.Results and Conclusions The pharmacokinetic parameters of iv thymopeptide in rabbit were:Cmax=(30.06±9.27)μg/ml,t1/2(β)=(29.24±23.78)min, Ke=(0.032 3±0.013 8)min-1 and AUC 0→∞=(205.63±46.48)μg*min/ml.
