Citicoline in treating neuroleptic-induced extrapyramidal side effect
- VernacularTitle:胞磷胆碱治疗药源性锥外系副作用
- Author:
Hexiang LIU
;
Ping CHENG
;
Shixun HUANG
;
Yiyun WANG
- Publication Type:Journal Article
- From:
Chinese Journal of New Drugs and Clinical Remedies
2001;20(3):185-187
- CountryChina
- Language:Chinese
-
Abstract:
AIM：To study the effects of citicoline in treating neuroleptic-induced extrapyramidal side effect (EPS)． METHODS：Seventy-five patients were divided into two groups：citicoline group of 38 patients ( M25，F13；age 28 a±s 9 a) received citicoline injection 0.5 g.d-1，in 5 % glucose injection 500 mL，iv，drip，qd ，for 14 d and control group of 37 patients ( M23，F14；age 27 a±6 a) received 5 % glucose injection 500 mL，iv, drip, qd，for 14 d． RESULTS: The total efficacy of citicoline or control group was 92 % and 11 % (P＜0.05 ), respectively．The tremour, muscular rigidity, gait and muscle dystonia were better in citicoline group than in control group. No side effects were found. CONCLUSION: Citicoline is effective for neuroleptic-induced EPS.
