Preparation and Clinical Use of Pefloxacin Mesylate Eye Drops
- VernacularTitle:甲磺酸培氟沙星滴眼液的研制及临床应用
- Author:
Weiping LIN
;
Wenting LIN
- Publication Type:Journal Article
- From:
China Pharmacy
2001;12(3):151-152
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE： To prepare pefloxacin mesylate eye drops.METHODS： The content of pefloxacin was determined with UV－ spectrophotometry.The therapeutic effect of the eye drops was observed in 170 out－ patients.RESULTS： The linearity range was 2～ 14μ g/ml with a regression equation of A=0.1 018C and r=0.9 999(n=7).The average recovery was 99.64％ with a RSD of 0.43％ .After treatment,150 out－ patients recovered,16 out－ patients improved and 4 out－ patients had no efficiency with a total effective rate of 97.6％ .CONCLUSION： The eye drops has definite therapeutic effect.The UV－ spectrophotometry method is simple,rapid and accurate in determination of the content and no special reagent is needed.
