Microvessel quantitation in colorectal tumors and metastasis
- VernacularTitle:大肠癌组织及转移瘤的微血管计数
- Author:
Yaxu WANG
;
Zengpeng LI
- Publication Type:Journal Article
- From:
Chinese Journal of General Surgery
2001;10(3):241-243
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the angiogenesis of colorectal tumors and the metastasis, and the relationsthip between microvessel with metastasis. Methods 15 colorectal tumors with lymph node and liver metastasis, 20 colorectal tumors without metastasis, and 20 nomal mucosa were studied imunohistochemically for microvessels quantitation. Results The mean vascular density (MVD) in colorectal tumors (56.17±8.31) and liver metastasis (94.26±10.46) were significantly higher than that in nomal mucosa (21.36±5.20)(P<0.01), the MVD in colorectal with metastas (90.27±7.16) were significantly higher than that in colorectal without metastasis (51.67±8.31) (P<0.01). Conclusions MVD can be used to evaluat the metastasis and as a prognostic factor in colorectal cancer patients.
