Local immune reaction cells in gastric carcinoma tissue
- VernacularTitle:胃癌的局部免疫细胞反应
- Author:
Hongchen ZHANG
;
Shuhua ZHANG
;
Fengguo BIAN
;
Yun MA
- Publication Type:Journal Article
- From:
Chinese Journal of General Surgery
2001;10(3):221-223
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the relationship between the biologic behaviours of gastric carcinoma (GC) and the immune reaction cells of GC tissue. Methods One hundred and seven radical gastrectomy specimens and 3 to 8 years follow-up data were quantitatively assessed on the reactive degree of lymph-plasma cells and eosinophils with CMIAS image analysis system. Mast cell reaction was accounted in the low power microscopy. Each indicator was divided into two groups, high reaction group and low reaction group, according to the intensity of reactions. Both high reaction and low reaction group were analysed on the base of clinicopathologic parameters. Results There was a significant difference in the survival time, depth of tumour invasion and lymph node metastasis in GC tissue between high reaction group and low reaction group (P<0.05). Conclusions Local immune reaction cells plays an important role in the defense mechanism of GC host against the tumour cells invising and spreading.
