A preliminary study on the toxin of earthworm and the methods to take it off
- VernacularTitle:蚯蚓毒素及其去除方法的初步研究
- Author:
Zuxun ZHANG
;
Liming HE
;
Peilan YU
;
Dianer YANG
;
Hua LIU
- Publication Type:Journal Article
- From:
Chinese Journal of Biochemical Pharmaceutics
2001;22(3):112-113
- CountryChina
- Language:Chinese
-
Abstract:
Purpose The source of earthworm toxin, its ingredients and the methods to take it off were studied.Methods The irritable secretor was dialyzed, and then examined by UV-Vis spectrum instrument.The proteins was analyzed with electrophoresis. The toxicity was tested in vivo.Results The proteins of irritable secretor 0.242mg/kg iv cause a mouse to death.Many bands were separated from the proteins with SDS-PAGE， among which two kinds were the principal. Even with different stimulus the secretor of earthworm was identical in ingredients.Conclusion The results demonstrated that the earthworm proteins of irritable secretion had toxicity and the toxin could be removed from earthworm by adding NaCl or 40V electricity.
