Influence of lanthanum nitrate on the expression of aquaporin 7 in the testis of rats
- VernacularTitle:硝酸镧对大鼠睾丸7型水通道基因表达的影响
- Author:
Danan LI
;
Baoxue YANG
;
Ke YANG
;
Yang LI
;
Xuejian ZHAO
;
Yuxiu NIE
;
Dong CHEN
- Publication Type:Journal Article
- From:
Chinese Journal of Pathophysiology
2001;17(3):238-240
- CountryChina
- Language:Chinese
-
Abstract:
AIM: To find out whether different dosage of rare earth element-lanthanum can influence the expression of aquaporin 7(AQP 7) in the testis of rats. METHODS:Rats were fed with lanthanum nitrate ［La(NO3)3］ and killed 6 months later. Testes were then removed immediately to extract total RNA. Northern blot analysis is performed finally. RESULTS:0.1 mg/kg La(NO3)3 depressed the expression of AQP 7 in rat testis, while 20 mg/kg La(NO3)3 had no significant effect on it. CONCLUSION: AQP 7 expession is found in the rat testis; La(NO3)3 can depress the expression of AQP 7 in the rat testis.
