Resolution of Optical Isomers of α-Hydroxy-acetones byHigh Resolution Gas Chromatography on Chiral Stationary Phase
- VernacularTitle:高分辩气相色谱法手性固定相拆分α-羟基酮光学异构体
- Author:
Yueqin ZHANG
;
Xueyan SHI
;
Ruonong FU
;
Hanbang ZHANG
;
Yun LING
;
Xiaobin ZUO
;
Hanfan LIU
- Publication Type:Journal Article
- From:
Chinese Journal of Analytical Chemistry
2001;29(3):336-338
- CountryChina
- Language:Chinese
-
Abstract:
Using the cyclodextrin bonded polysiloxane (bikis〔（2,6-di-O-pentyl-3-O-hex-6-O-enyl)-pentakis(2,6-di-O-pentyl-3-O-methyl)-β-cyclodextrm-polysiloxane〕) as gas chromatographic stationary phase, α-hydroxy acetones were separated and the values of the enantiomeric excess(e.e) of 3-hydroxy-2-butanone were determined. The results showed that the high resolution gas chromatography (HRGC) using the chiral gas chromatographic stationary phase could determine the productive rate of the asymmetric hydrogenaton reaction and evaluate the enantoselectivity of the catalyst system.
