CYCLOARTANE TRITERPENES AND GLYCOSIDES FROM CIMICIFUGA ACERINA
- VernacularTitle:小升麻中的环菠萝蜜烷型三萜及其糖苷成分
- Author:
Qingwen ZHANG
;
Wencai YE
;
Chuntao CHE
;
Shouxun ZHAO
- Publication Type:Journal Article
- From:
Acta Pharmaceutica Sinica
2001;36(4):287-291
- CountryChina
- Language:Chinese
-
Abstract:
AIM To investigate the chemical constituents from the rhizomes of Cimicifuga acerina (Sieb. et Zucc.) Tanaka. METHODS Column chromatgraphy (including silica gel and ODS) together with HPLC was used to separate the chemical constituents whose structures were determined by FAB-MS, NMR (1D and 2D) and hydrolysis methods. RESULTS Five cycloartane triterpenoids were isolated and identified as: (22R)-22-hydroxycimigenol (I), (22R)-22-hydroxy-24-O-acetylhydroshengmanol 3-O-β-D-xylopyranoside (II), dahurinol (III), 24-epi-24-O-acetyl-7,8-didehydroshengmanol 3-O-β-D-xylopyranoside (IV), 25-O-acetyl-7,8-didehydrocimigenol 3-O-β-D-xylopyranoside (V). CONCLUSION Compound I is a new natural product, compound II is a new compound and compounds IV and V were isolated from this plant for the first time.
