Isolation of alkaloids and structure elucidation of lehmannine from
- VernacularTitle:苦豆子种子中生物碱的分离及lehmannine的结构确定
- Author:
Bin LIU
;
Jinliang LI
;
Yingjin YUAN
- Publication Type:Journal Article
- Keywords:
Sophora alopecuroides L.;
alkaloids;
lehmannine (12,13-dehydromatrine)
- From:
Chinese Traditional and Herbal Drugs
2001;32(4):293-296
- CountryChina
- Language:Chinese
-
Abstract:
To study the alkaloid constituents in the seed of Sophora alopecuroides L. and isolation of lehmannine by transhydrogenation of sophocarbine to matrine present in the mixture. Methods Various processes of exchange, ion exchange and column chromatograph with very similar physical and chemical properties was successfully separated by transhydrogenation. Results 5 alkaloids were obtained and identified by elementary analysis, IR, MS, 1HNMR and 13CNMR as oxymatrine, oxysophoridine, matrine, sophoridine and lehmannine (12, 13-dehydromatrine). Conclusion Lehmannine was isolated from the seed of S. alopecuroides for the first time.
