Studies on biopharmacy of ultra-fine particles of Atractylodes lancea, Phellodendron chinense and a pill composed of the two drugs Ⅰ. Characterization by scanning electron microscopy
- VernacularTitle:苍术、黄柏及二妙丸超细微粉的生物药剂学的研究
- Author:
Wanqin JIN
;
Liwei GUO
;
Fang HUANG
- Publication Type:Journal Article
- Keywords:
ultra-fine herbal particles;
scanning electron microscope;
Atractylodes lancea (Thunb.) DC.;
Phellodendron chinense Schneid;
ERMIAO PILL
- From:
Chinese Traditional and Herbal Drugs
2001;32(4):306-308
- CountryChina
- Language:Chinese
-
Abstract:
To characterize the ultra-fine particles of Atractylodes lancea (Thunb.) DC., Phellodendron chinense Schneid and the ERMIAO PILL*, a compounded preparation of the above two drugs, for the purpose to observe a deeper view on their physico-chemical properties. Methods By comparing their particle size, porosity and specific surface area with light and scanning electron microscope. Results The size of the ultra-fine particles were more uniform in size, 90% of which were under 20 μm, their specific area were increased by 60% ～ 190% and bulk density were around 0.42 g/cm3, and the great majority of the plant cells were broken as compared with the conventional coarse powder. Conclusion Both A. lancea and P. chinense together with their combined preparation became smaller in particle size, more uniformly distributed with increased specific surface area and broken cell wall.
