Chiral Resolution of Optical Isomers of α-Chloro-N-phenyl propanamide by Reversed Phase HighPerformance Liquid Chromatography
- VernacularTitle:反相高效液相色谱法拆分α-氯代丙酰替苯胺光学异构体
- Author:
Jiehua SHI
;
Xiuzhu XU
;
Gensheng YANG
- Publication Type:Journal Article
- From:
Chinese Journal of Analytical Chemistry
2001;29(4):431-433
- CountryChina
- Language:Chinese
-
Abstract:
The chiral resolution of the optical isomers of aryloxypropionic acid herbicide intermediate α-chloro-N-phenyl propanamide was studied by reversed phase high performance liquid chromatography on chiral column. The experimental results showed that the optical isomers of α-chloro-N-phenyl propanamide could be resolved much better on the tribenzoylcellulose (CTB) chiral column with ethanol as mobile phase. The separation factor and separation degree were 1.52 and 0.60 respectively
