Molecular Mechanisms of Neutrophil Activation in Acute Lung Injury.
10.4046/trd.2002.53.6.595
- Author:
Ho Kee YUM
1
Author Information
1. Department of Internal Medicine, School of Medicine, Inje University, Seoul, Korea. pulho@korea.com
- Publication Type:Review
- Keywords:
Acute lung injury;
Neutrophil;
Signal transduction
- MeSH:
Abbreviations;
Acute Lung Injury*;
Carrier Proteins;
Granulocyte Colony-Stimulating Factor;
Interleukins;
Leukocyte Elastase;
Macrophages;
N-Formylmethionine Leucyl-Phenylalanine;
NADP;
Neutrophil Activation*;
Neutrophils*;
NF-kappa B;
Nitric Oxide Synthase;
p21-Activated Kinases;
p38 Mitogen-Activated Protein Kinases;
Peroxidase;
Phosphatidylinositol 3-Kinase;
Phosphotransferases;
Platelet Activating Factor;
Protein Kinases;
Protein-Tyrosine Kinases;
Proto-Oncogene Proteins c-akt;
Reactive Oxygen Species;
Respiratory Distress Syndrome, Adult;
Response Elements;
Signal Transduction;
Tumor Necrosis Factor-alpha
- From:Tuberculosis and Respiratory Diseases
2002;53(6):595-611
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
ABBREVIATIONS: Akt/PKB protein kinase B, ALI acute lung injury, ARDS acute respiratory distress syndrome, CREB C-AMP response element binding protein, ERK extracelluar signal-related kinase, fMLP fMet-Leu-Phe, G-CSF granulocyte colony-stimulating factor, IL interleukin, ILK integrin-linked kinase, JNK Jun N-terminal kinase, LPS lipopolysaccharide, MAP mitogen-activated protein, MEK MAP/ERK kinase, MIP-2 macrophage inflammatory protein-2, MMP matrix metalloproteinase, MPO myeloperoxidase, NADPH nicotinamide adenine dinucleotide phosphate, NE neutrophil elastase, NF-kappaB nuclear factor-kappa B, NOS nitric oxide synthase, p38 MAPK p38 mitogen activated protein kinase, PAF platelet activating factor, PAKs p21-activated kinases, PMN polymorphonuclear leukocytes, PI3-K phosphatidylinositol 3-kinase, PyK proline-rich tyrosine kinase, ROS reactive oxygen species, TNF-alpha tumor necrosis factor-alpha.
