Clinical Analysis of 102 Cases of ARDs Induced by Angiotension Converting Enzyme Inhibitors
- VernacularTitle:血管紧张素转化酶抑制剂致不良反应 102例分析
- Author:
Yongxin LI
;
Zhiyuan SONG
;
Songqing LIU
- Publication Type:Journal Article
- From:
China Pharmacy
2001;12(5):298-299
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE： To analysis the adverse reactions of angiotension converting enzyme inhibitor（ ACEI） ， so as to deepen the understanding to the ARDs and improve the therapeutic effect of ACEI METHODS： The therapeutic effects and ARDs of ACEI were retrospectively reviewed and the incidence of ARDs induced by ACEI and the relationship between different ACEIs and their ARDs were analyzed RESULTS： （ 1） The incidence of ARDs of ACEI was 12％ Stimulating cough， parageusia， gastrointestinal tract discomfort， skin rash， itch of skin， hypotension， headache， dizziness， proteinuria and angioedema were the common symptoms （ 2） Of five kinds of ACEIs， captopril induced the highest incidence of ARDs and stimulating cough， parageusia， gastrointestinal tract discomfort， skin rash and itch of skin were the most common manifestations CONCLUSION： Stimulating cough， parageusia， gastrointestinal tract discomfort and skin rash are the most common symptoms of ARDs， and the symptoms will disappear when drug administration is discontinued
