Effects of Nabumetone on Immunological Functions in Mice
- VernacularTitle:萘丁美酮对小鼠免疫功能的影响
- Author:
Shiwen ZHOU
;
Ping YAO
;
Qinshu KANG
- Publication Type:Journal Article
- From:
China Pharmacy
2001;12(5):268-269
- CountryChina
- Language:Chinese
-
Abstract:
AIM： To study the effects of nabumetone on immunological fuctions in mice METHODS： After nabumetone was given ig to mice， the weight of thymus and spleen， phagocytizing function of macrophages， PHA－ induced lymphocyte transformation were observed respectively in mice RESULTS： The weight of thymus and spleen was decreased， the phagocytizing function of macrophages was reduced， PHA－ induced lymphocyte transformation was markedly inhibited with nabumetone in mice CONCLUSION： The immunological function in mice was significantly inhibited with nonsteriod anti－ inflammatory drug－ nabumetone
