Experimental Studies on the Preventive and Therapeutic Effects of Yingganfukang on Hepatocirrhosis
- VernacularTitle:硬肝复康防治肝硬化的初步实验研究
- Author:
Tianran WANG
;
Guang XU
;
Xiangyuan ZENG
;
Buren MA
- Publication Type:Journal Article
- From:
China Pharmacy
2001;12(5):270-271
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE： The preventive and therapeutic effects of a compound traditional Chinese medicine preparation， Yingganfukang(YGFK)， on mice experimental liver fibrosis were studied METHODS： The acute liver damage and fibrosis rat models were established by giving single or multi－ dose of CCl4 orally and the liver dysimmunity model was established by giving BCG and LPS intravenously Rats were divided into YGFK group and control group The serum ALT， AST and ALP of the mice were examined The liver tissues taken from the liver fibrosis mice were committed to pathological examination RES_ ULTS： The serum ALT， ALP of the YGFK(2g/kg· d) group and control group were （ 6 153± 3 491） IU/L、 （ 202± 24） IU/L and （ 9 275± 2 744） IU/L、 （ 421± 67） IU/L， respectively in the acute liver damage mice with significant differences
